Cover image for Organic chemistry
Organic chemistry
2nd ed.
Publication Information:
Oxford ; New York : Oxford University Press, ©2012.


Physical Description:
xxv, 1234 pages : illustrations (some color) ; 28 cm
General Note:
Revised edition of: Organic chemistry / Jonathan Clayden [and others].
Determining reaction mechanisms -- There are mechanisms and there are mechanisms -- Determining reaction mechanisms: the Cannizzaro reaction -- Be sure of the structure of the product -- Systematic structural variation -- The Hammett relationship -- Other kinetic evidence for reaction mechanisms -- Acid and base catalysis -- The detection of intermediates -- Stereochemistry and mechanism -- Summary of methods for the investigation of mechanism -- Further reading -- Organometallic chemistry -- Transition metals extend the range of organic reactions -- The 18 electron rule -- Bonding and reactions in transition metal complexes -- Palladium is the most widely used metal in homogeneous catalysis -- The Heck reaction couples together an organic halide or triflate and an alkene -- Cross-coupling of organometallics and halides -- Allylic electrophiles are activated by palladium(O) -- Palladium-catalysed amination of aromatic rings -- Alkenes coordinated to palladium(II) are attacked by nucleophiles -- Palladium catalysis in the total synthesis of a natural alkaloid -- An overview of some other transition metals -- Further reading -- Asymmetric synthesis -- Nature is asymmetric -- The chiral pool: Nature's chiral centres `off the shelf' -- Resolution can be used to separate enantiomers -- Chiral auxiliaries -- Chiral reagents -- Asymmetric catalysis -- Asymmetric formation of carbon-carbon bonds -- Asymmetric aldol reactions -- Enzymes as catalysts -- Further reading -- Organic chemistry of life -- Primary metabolism -- Life begins with nucleic acids -- Proteins are made of amino acids -- Sugars -- just energy sources? -- Lipids -- Mechanisms in biological chemistry -- Natural products -- Fatty acids and other polyketides are made from acetyl CoA -- Terpenes are volatile constituents of plants -- Further reading -- Organic chemistry today -- Science advances through interaction between disciplines -- Chemistry vs viruses -- The future of organic chemistry -- Further reading.
A first- and second-year undergraduate organic chemistry textbook, specifically geared to British and European courses and those offered in better schools in North America, this text emphasises throughout clarity and understanding.

Inspiring and motivating students from the moment it published, Organic Chemistry has established itself in just one edition as the student's choice of an organic chemistry text. The second edition refines and refocuses Organic Chemistry to produce a text that is even more student-friendly, coherent, and logical in its presentation than before. Like the first, the second edition is built on three principles: An explanatory approach, through which the reader is motivated to understand the subject and not just learn the facts; A mechanistic approach, giving the reader the power to understand compounds and reactions never previously encountered; An evidence-based approach, setting out clearly how and why reactions happen as they do, giving extra depth to the reader's understanding. The authors write clearly and directly, sharing with the reader their own fascination with the subject, and leading them carefully from topic to topic. Their honest and open narrative flags pitfalls and misconceptions, guiding the reader towards a complete picture of organic chemistry and its universal themes and principles. --! From publisher's description.
Added Uniform Title:
Organic chemistry.