Ignatius J. Reilly of New Orleans, --selfish, domineering, deluded, tragic and larger than life-- is a noble crusader against a world of dunces. He is a modern-day Quixote beset by giants of the modern age. In magnificent revolt against the twentieth century, Ignatius propels his monstrous bulk among the flesh posts of the fallen city, documenting life on his Big Chief tablets as he goes, until his maroon-haired mother decrees that Ignatius must work....

Over the course of two days, Odd Thomas, his soulmate Stormy Llewellyn, and an assortment of allies make their way through a dark, terrifying world in which past and present, and life and death collide as they try to avert a cataclysm.

The story of young Tristran Thorn and his adventures in the land of Faerie. He has fallen in love with beautiful Victoria Forester and in order to win her hand, he must retrieve a fallen star and deliver it to her.

Amanda, a faded southern belle, abandoned wife, and dominating mother, hopes to match her daughter Laura with an eligible "gentleman caller" while her son Tom supports the family. Laura, lame and painfully shy, evades her mother's schemes and reality by retreating to the make-believe world of her glass animal collection. Tom eventually leaves home to become a writer but is forever haunted by the memory of Laura.

Ten-year-old message-runner Freddie Musgrove's silence is bought after he witnesses a scene of unremitting horror at The Towers, but years later, when the horror reoccurs, Freddie must fight to remain uninvolved.