The mythical world starts a rebellion against humanity in order to rule the Earth. Hellboy and his team returns and they must save the world from the mythical creatures. Now, as the creatures who inhabit the spiritual realm get ready for an all out attack on humans, the only one capable of saving the Earth is a tough-talking hellspawn rejected by both worlds.

In the 1940s, the Third Reich has joined forces with the evil Grigori Rasputin, who has used his occult powers to summon up a demon from the depths of Hell. However, the demonic creature is captured by American forces, and put in the care of Professor Broom. Under Broom's care, Hellboy develops the desire to do good. Sixty years later he takes action as part of an elite secret defense team alongside Liz Sherman, and Abe Sapian, an aquatic humanoid...

In the 1940s, the Third Reich has joined forces with the evil Grigori Rasputin, who has used his occult powers to summon up a demon from the depths of Hell. However, the demonic creature is captured by American forces, and put in the care of Professor Broom. Under Broom's care, Hellboy develops the desire to do good. Sixty years later he takes action as part of an elite secret defense team alongside Liz Sherman, and Abe Sapian, an aquatic humanoid...

The fate of humanity hangs in the balance when a ruthless prince awakens an unstoppable army of creatures and wages war with the human world. It's up to Hellboy and his team of paranormal outcasts to face off with the forces of darkness in the ultimate battle of good versus evil!