From the Book - Large Print - Large print edition.
1 One Hundred Years Young p. 23 --
Mysteries of Aging p. 28 --
What Makes SuperAgers Stay Healthy? p. 33 --
Studying Centenarians p. 37 --
Designing a Study Without a Control Group p. 48 --
Meeting Our First AJ Centenarians and Their Offspring p. 52 --
A Perfect Genome? p. 56 --
Centenarians' Interactions with Their Environments p. 58 --
Do as I Say, Not as I Do p. 70 --
Search for Protection from Aging p. 90 --
Eating Less May Lead to More Healthy Years p. 97 --
Unlocking the Secrets in Fat p. 99 --
Caloric Restriction: A Mixed Bag of Effects p. 109 --
Aging Begins Before We're Born p. 114 --
SuperAgers' Top Secrets p. 115 --
3 Cholesterol: Is More Better? p. 119 --
Unlocking Cholesterol's Longevity Secrets p. 124 --
Are There Really Good Gene Mutations? p. 129 --
Solving the Mystery of Helpful Gene Mutations p. 132 --
Benefits of CETP Personified p. 140 --
A Mutation That Adds Years to Life Span? p. 146 --
4 Growth Hormone: Less Is More p. 149 --
Less Growth May Lead to an Exceptionally Long Life p. 151 --
Growth Hormone Clues from Our Centenarians p. 154 --
Epigenetic Mechanisms Can Increase Longevity p. 163 --
Making the Most of Our Findings p. 169 --
Growth Hormones Don't "Grow" Life Span p. 173 --
5 Unraveling the Longevity Mystery Deep Inside Our Cells p. 177 --
A Match Made on Earth p. 178 --
Mitochondria's Hidden Purpose p. 180 --
Resilient to the End p. 187 --
A CohBar Is Born p. 198 --
Searching for Promising Peptides p. 204 --
6 Quest to Prove Aging Can Be Targeted p. 209 --
Choosing an Existing Drug to Prove Our Point p. 220 --
Getting the FDA on Board p. 225 --
How the TAME Study Works p. 228 --
Who's Going to Pay for All of This? p. 235 --
Metformin Is the Tool, Not the Goal p. 241 --
7 Making Eighty the New Sixty p. 245 --
Price of Progress p. 253 --
Collaboration Is the Key to Speed p. 254 --
Long, Healthy Life Span Versus Immortality p. 258 --
Gap Between Making Drugs and Making Drugs Available p. 265 --
8 Stop the Clock p. 268 --
How Old Is Old? p. 271 --
Use It or Lose It p. 275 --
Antioxidants and Hormesis p. 279 --
Thriving in the Shadow of Stress p. 282 --
Preventing the Loss of Muscle Mass as We Age p. 288 --
Exercise Plus Metformin p. 289 --
Feeding Our Longevity p. 291 --
Hydrating Wisely p. 297 --
Prevent Obesity p. 299 --
Nutraceuticals Are in the Works p. 305 --
Magic Pills We've Been Wishing For p. 310 --
When We Eat Matters p. 313 --
Our DNA Has Something to Say p. 321 --
Stay Mentally Sharp p. 326 --
Other Promising Practices p. 336 --
How to Decide What's Good for You p. 341 --
9 Bright Horizons p. 343 --
Unparalleled Power of Omics p. 344 --
Personalized Medicine p. 350 --
Advances in Early Detection p. 352 --
Pioneering Explorations p. 354 --
Reversing Cellular Age p. 358 --
Genetic Engineering p. 360.